DEVELOPMENTALLY REGULATED POST-TRANSLATIONAL MODIFICATION OF NUCLEOPLASMIN CONTROLS HISTONE SEQUESTRATION AND DEPOSITION

Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos.During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic Sunglasses epigenome.Here, we demonstrate that Xenopus laevis Npm post-translational modification

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A spring forward for hominin evolution in East Africa.

Groundwater is essential to modern human survival during drought periods.There is also growing geological evidence of springs associated with stone tools and hominin fossils in the Brush Roller Drive Gear East African Rift System (EARS) during a critical period for hominin evolution (from 1.8 Ma).However it is not known how vulnerable these springs

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New technologies for low-grade glioma surgery

Brain surgery has come far from the primitive methods used thousands of years ago.In the last hundred years alone, we have come across countless breakthroughs like the invention of bipolar coagulation, the surgical microscope, microsurgical techniques and a large variety of surgical instruments.The latest years have brought us neuro-navigation, MET

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Some environmental and biological factors influencing the activity of entomopathogenic Bacillus on mosquito larvae in Brazil

METAL The influence of environmental and biological factors on the efficacy of Bacillus thuringiensis serovar israelensis and B.sphaericus as mosquito larvicides are reviewed.The importance of strain dependence, cultivating media/methods, mosquito species/specificity, formulations and their relation to mosquito feeding habits, as well as temperatur

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